Duration of intravenous antibiotics for patients with neutropenic fever

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blood culture in neutropenic patients with fever

in 2004, klastersky et al. reported that fever isa common finding in patients with hematologicmalignancies, occurring in more than 80% of thepatients during or after chemotherapy.[1] he andhis colleagues also reported that the most fearedinfection in neutropenic patients is bloodstreaminfection (bsi), which significantly increases themortality rate of these patients.[2] in 2009, viscoliet al.[3...

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Intravenous Itraconazole vs. Amphotericin B Deoxycholate for Empirical Antifungal Therapy in Patients with Persistent Neutropenic Fever

BACKGROUND Amphotericin B dexoycholate is currently the standard empirical antifungal therapy for neutropenic patients with hematologic malignancies and who also have persistent fever that does not respond to antibacterial therapy. The antifungal triazoles offer a potentially safer and effective treatment alternative to Amphotericin B dexoycholate. METHODS We assessed the efficacy and safety ...

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Randomized trial of oral versus intravenous antibiotics in low-risk febrile neutropenic patients with lung cancer.

BACKGROUND Neutropenic fever is one of the most serious adverse effects of cancer chemotherapy. Neutropenia may cause a life-threatening bacterial infection. Therefore, febrile neutropenic inpatients are empirically treated with intravenous broad-spectrum antibiotics. Recently, several studies have suggested the presence of low-risk groups among febrile neutropenic patients. METHODS A prospec...

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Serum cholesterol levels in neutropenic patients with fever.

Hypocholesterolemia, which often accompanies infectious diseases has been suggested to serve as a prognostic marker in hospitalized patients. Even though patients with chemotherapy-induced leukopenia are at high risk of infection and mortality, only limited information is available on serum cholesterol levels in these patients. We therefore measured serum cholesterol levels in 17 patients with ...

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Management of Neutropenic Fever

Febrile neutropenia is a frequent complication in hematology-oncology, BMT, and solid organ transplantation. Approximately 50% of those who develop febrile neutropenia have a documented or occult infection. Febrile patients with severe neutropenia (<100/mm3) have bacteremia in up to 20% of cases. Initial evaluation should include careful history and physical examination with particular attentio...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 1994

ISSN: 0923-7534

DOI: 10.1093/oxfordjournals.annonc.a058877